Chapter 1In this chapter, the authors discuss the fundamentals of metabolism. Metabolism is defined as the sum of all biochemical reactions that occur in a living cell. It is the process by which energy is converted from one form to another and used for various cellular processes, such as growth, development, and maintenance. Through metabolism, cells can break down glucose into ATP, which is then used for energy. Additionally, proteins, carbohydrates, and fats are broken down into metabolites that can be used for energy production or as building blocks for synthesis. The authors also discuss how different metabolic pathways are interconnected, and how enzymes, hormones, and other factors influence the rate and outcome of these pathways.
Chapter 2The second chapter focuses on how metabolic rate is determined. The authors explain that metabolism is affected by the body’s size and structure, the type and amount of food consumed, and the external environment. They also describe how the hormones adrenaline and cortisol can influence the metabolic rate, as well as how genetic factors influence the rate and type of metabolism. Examples are given to illustrate how increased physical activity, different diets, and certain medications can affect the body’s metabolism.
Chapter 3In this chapter, the authors discuss the disorders and diseases associated with metabolic dysfunctions. They discuss how genetics, diet, and lifestyle contribute to different metabolic diseases such as obesity, diabetes, and cardiovascular disease. They describe the structure of the main metabolic enzymes and how mutations and genetic diseases affect their structure and function, leading to metabolic dysfunctions. Examples are given to illustrate how epigenetic and environmental influences can alter gene expression, leading to metabolic disorders.
Chapter 4The fourth chapter discusses nutritional interventions and their effect on metabolism. The authors explain that proper nutrition is essential for maintaining a healthy metabolic rate, and they describe how different nutrients, such as proteins, carbohydrates, and fats, are metabolized in the body. They also discuss dietary interventions such as calorie-restriction and low-carbohydrate diets, and how they can be used to modify the rate of metabolism.
Chapter 5The fifth and final chapter of Metabolical focuses on the potential medical applications of metabolism as a therapeutic approach. Specifically, the authors discuss how the manipulation of specific metabolic pathways can be used to treat various diseases. They describe how drugs and other therapies, such as gene therapy, can be used to modulate the activity of enzymes involved in biochemical pathways. Additionally, the authors review the evidence for metabolic therapies in the treatment of several diseases, such as cancer, diabetes, and obesity. They also discuss the potential for new therapeutic applications in the future.
